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pentobarbital will lessen the extent or result of estradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.Check Closely (1)pentobarbital will minimize the extent or influence of mestranol by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the extent or outcome of levoketoconazo